| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_04550 | ISM_08440 | ISM_04550 | ISM_08440 | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | COG3145 Alkylated DNA repair protein. | 0.430 |
| ISM_04550 | ISM_10226 | ISM_04550 | ISM_10226 | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | ADA regulatory protein; COG2207 AraC-type DNA-binding domain-containing proteins. | 0.696 |
| ISM_08440 | ISM_04550 | ISM_08440 | ISM_04550 | COG3145 Alkylated DNA repair protein. | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | 0.430 |
| ISM_08440 | ISM_08445 | ISM_08440 | ISM_08445 | COG3145 Alkylated DNA repair protein. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.697 |
| ISM_08440 | ISM_08450 | ISM_08440 | ISM_08450 | COG3145 Alkylated DNA repair protein. | Glutamate dehydrogenase. | 0.441 |
| ISM_08440 | ISM_10226 | ISM_08440 | ISM_10226 | COG3145 Alkylated DNA repair protein. | ADA regulatory protein; COG2207 AraC-type DNA-binding domain-containing proteins. | 0.505 |
| ISM_08440 | dnaJ | ISM_08440 | ISM_08460 | COG3145 Alkylated DNA repair protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.408 |
| ISM_08440 | dnaK | ISM_08440 | ISM_08455 | COG3145 Alkylated DNA repair protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.518 |
| ISM_08445 | ISM_08440 | ISM_08445 | ISM_08440 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | COG3145 Alkylated DNA repair protein. | 0.697 |
| ISM_08445 | ISM_08450 | ISM_08445 | ISM_08450 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | Glutamate dehydrogenase. | 0.474 |
| ISM_08450 | ISM_08440 | ISM_08450 | ISM_08440 | Glutamate dehydrogenase. | COG3145 Alkylated DNA repair protein. | 0.441 |
| ISM_08450 | ISM_08445 | ISM_08450 | ISM_08445 | Glutamate dehydrogenase. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.474 |
| ISM_10226 | ISM_04550 | ISM_10226 | ISM_04550 | ADA regulatory protein; COG2207 AraC-type DNA-binding domain-containing proteins. | DNA-3-methyladenine glycosylase II, putative; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase. | 0.696 |
| ISM_10226 | ISM_08440 | ISM_10226 | ISM_08440 | ADA regulatory protein; COG2207 AraC-type DNA-binding domain-containing proteins. | COG3145 Alkylated DNA repair protein. | 0.505 |
| dnaJ | ISM_08440 | ISM_08460 | ISM_08440 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | COG3145 Alkylated DNA repair protein. | 0.408 |
| dnaJ | dnaK | ISM_08460 | ISM_08455 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| dnaK | ISM_08440 | ISM_08455 | ISM_08440 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | COG3145 Alkylated DNA repair protein. | 0.518 |
| dnaK | dnaJ | ISM_08455 | ISM_08460 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.999 |