| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_06675 | ISM_08575 | ISM_06675 | ISM_08575 | Phosphate acetyltransferase; COG0281 Malic enzyme. | L-lactate dehydrogenase, putative; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | 0.668 |
| ISM_06675 | ISM_08580 | ISM_06675 | ISM_08580 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | 0.473 |
| ISM_06675 | ISM_08585 | ISM_06675 | ISM_08585 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins. | 0.579 |
| ISM_06675 | ISM_09586 | ISM_06675 | ISM_09586 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.786 |
| ISM_08575 | ISM_06675 | ISM_08575 | ISM_06675 | L-lactate dehydrogenase, putative; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.668 |
| ISM_08575 | ISM_08580 | ISM_08575 | ISM_08580 | L-lactate dehydrogenase, putative; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | 0.586 |
| ISM_08575 | ISM_08590 | ISM_08575 | ISM_08590 | L-lactate dehydrogenase, putative; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | ephB, putative; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.424 |
| ISM_08575 | ISM_09586 | ISM_08575 | ISM_09586 | L-lactate dehydrogenase, putative; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.874 |
| ISM_08580 | ISM_06675 | ISM_08580 | ISM_06675 | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.473 |
| ISM_08580 | ISM_08575 | ISM_08580 | ISM_08575 | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | L-lactate dehydrogenase, putative; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | 0.586 |
| ISM_08580 | ISM_08585 | ISM_08580 | ISM_08585 | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins. | 0.493 |
| ISM_08580 | ISM_08590 | ISM_08580 | ISM_08590 | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | ephB, putative; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.401 |
| ISM_08580 | ISM_09586 | ISM_08580 | ISM_09586 | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.473 |
| ISM_08580 | ISM_11660 | ISM_08580 | ISM_11660 | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | Phosphate transporter family protein; COG0306 Phosphate/sulphate permeases. | 0.469 |
| ISM_08580 | ISM_16615 | ISM_08580 | ISM_16615 | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | Potassium uptake transporter, NAD-binding subunit, TrkA; COG0569 K+ transport systems, NAD-binding component. | 0.607 |
| ISM_08580 | ISM_17225 | ISM_08580 | ISM_17225 | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components. | 0.708 |
| ISM_08580 | cysC | ISM_08580 | ISM_11065 | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.604 |
| ISM_08585 | ISM_06675 | ISM_08585 | ISM_06675 | Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.579 |
| ISM_08585 | ISM_08580 | ISM_08585 | ISM_08580 | Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins. | Sulfur deprivation response regulator; COG0471 Di- and tricarboxylate transporters. | 0.493 |
| ISM_08585 | ISM_08590 | ISM_08585 | ISM_08590 | Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins. | ephB, putative; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.613 |