node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ISM_01375 | argH | ISM_01375 | ISM_08605 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | COG0165 Argininosuccinate lyase. | 0.442 |
ISM_01375 | asd | ISM_01375 | ISM_02370 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.995 |
ISM_01375 | dapA | ISM_01375 | ISM_02305 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.725 |
ISM_01375 | dapB | ISM_01375 | ISM_06420 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.862 |
ISM_01375 | dapF | ISM_01375 | ISM_02695 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.563 |
ISM_01375 | lysA | ISM_01375 | ISM_08620 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.811 |
ISM_01375 | murE | ISM_01375 | ISM_00140 | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.442 |
ISM_07700 | lysA | ISM_07700 | ISM_08620 | Saccharopine dehydrogenase, putative; COG0686 Alanine dehydrogenase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.855 |
ISM_08625 | argH | ISM_08625 | ISM_08605 | Hypothetical protein. | COG0165 Argininosuccinate lyase. | 0.521 |
ISM_08625 | lysA | ISM_08625 | ISM_08620 | Hypothetical protein. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.772 |
argH | ISM_01375 | ISM_08605 | ISM_01375 | COG0165 Argininosuccinate lyase. | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.442 |
argH | ISM_08625 | ISM_08605 | ISM_08625 | COG0165 Argininosuccinate lyase. | Hypothetical protein. | 0.521 |
argH | asd | ISM_08605 | ISM_02370 | COG0165 Argininosuccinate lyase. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.507 |
argH | dapA | ISM_08605 | ISM_02305 | COG0165 Argininosuccinate lyase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.465 |
argH | dapB | ISM_08605 | ISM_06420 | COG0165 Argininosuccinate lyase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.608 |
argH | dapF | ISM_08605 | ISM_02695 | COG0165 Argininosuccinate lyase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.516 |
argH | lysA | ISM_08605 | ISM_08620 | COG0165 Argininosuccinate lyase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.879 |
asd | ISM_01375 | ISM_02370 | ISM_01375 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family. | 0.995 |
asd | argH | ISM_02370 | ISM_08605 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | COG0165 Argininosuccinate lyase. | 0.507 |
asd | dapA | ISM_02370 | ISM_02305 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.980 |