| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_04670 | ISM_08325 | ISM_04670 | ISM_08325 | COG1960 Acyl-CoA dehydrogenases. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.606 |
| ISM_04670 | ISM_08695 | ISM_04670 | ISM_08695 | COG1960 Acyl-CoA dehydrogenases. | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.561 |
| ISM_08325 | ISM_04670 | ISM_08325 | ISM_04670 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG1960 Acyl-CoA dehydrogenases. | 0.606 |
| ISM_08325 | ISM_08695 | ISM_08325 | ISM_08695 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.532 |
| ISM_08325 | ISM_08700 | ISM_08325 | ISM_08700 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.782 |
| ISM_08325 | ISM_08720 | ISM_08325 | ISM_08720 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.653 |
| ISM_08695 | ISM_04670 | ISM_08695 | ISM_04670 | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | COG1960 Acyl-CoA dehydrogenases. | 0.561 |
| ISM_08695 | ISM_08325 | ISM_08695 | ISM_08325 | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.532 |
| ISM_08695 | ISM_08700 | ISM_08695 | ISM_08700 | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | 0.865 |
| ISM_08695 | ISM_08705 | ISM_08695 | ISM_08705 | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | HAD-superfamily hydrolase, subfamily IA, variant 1 family protein; COG1011 Predicted hydrolase (HAD superfamily). | 0.863 |
| ISM_08695 | ISM_08710 | ISM_08695 | ISM_08710 | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.773 |
| ISM_08695 | ISM_08715 | ISM_08695 | ISM_08715 | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | COG1671 Uncharacterized protein conserved in bacteria; Belongs to the UPF0178 family. | 0.635 |
| ISM_08695 | ISM_08720 | ISM_08695 | ISM_08720 | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.629 |
| ISM_08695 | ISM_08725 | ISM_08695 | ISM_08725 | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | S-formylglutathione hydrolase, putative; Serine hydrolase involved in the detoxification of formaldehyde. | 0.657 |
| ISM_08695 | ISM_16195 | ISM_08695 | ISM_16195 | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | COG0236 Acyl carrier protein. | 0.634 |
| ISM_08695 | acpP | ISM_08695 | ISM_01130 | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.634 |
| ISM_08700 | ISM_08325 | ISM_08700 | ISM_08325 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.782 |
| ISM_08700 | ISM_08695 | ISM_08700 | ISM_08695 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). | 0.865 |
| ISM_08700 | ISM_08705 | ISM_08700 | ISM_08705 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | HAD-superfamily hydrolase, subfamily IA, variant 1 family protein; COG1011 Predicted hydrolase (HAD superfamily). | 0.845 |
| ISM_08700 | ISM_08710 | ISM_08700 | ISM_08710 | Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.773 |