Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_08700Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. (305 aa)    
Predicted Functional Partners:
ISM_08695
Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
    
  0.865
ISM_08705
HAD-superfamily hydrolase, subfamily IA, variant 1 family protein; COG1011 Predicted hydrolase (HAD superfamily).
       0.845
ISM_14535
COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.
 
  
 0.816
ISM_14525
COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.
  
  
  0.794
ISM_08325
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.782
ISM_08710
Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.
       0.773
ISM_08250
COG3938 Proline racemase; Belongs to the proline racemase family.
 
  
 0.714
ISM_08715
COG1671 Uncharacterized protein conserved in bacteria; Belongs to the UPF0178 family.
       0.655
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
     
 0.613
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
     
 0.613
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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