Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_08735Putative transporter, AEC family protein; COG0679 Predicted permeases. (310 aa)    
Predicted Functional Partners:
ISM_08725
S-formylglutathione hydrolase, putative; Serine hydrolase involved in the detoxification of formaldehyde.
       0.834
ISM_08730
Nitroreductase family protein; COG0778 Nitroreductase.
       0.806
ISM_08715
COG1671 Uncharacterized protein conserved in bacteria; Belongs to the UPF0178 family.
       0.648
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
  
  
 0.603
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
  
  
 0.603
ISM_08705
HAD-superfamily hydrolase, subfamily IA, variant 1 family protein; COG1011 Predicted hydrolase (HAD superfamily).
       0.541
ISM_08700
Ornithine cyclodeaminase/mu-crystallin family protein; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.
       0.539
ISM_08740
Hypothetical protein.
       0.536
ISM_08720
Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
  
    0.532
ISM_08695
Putative alpha/beta hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
       0.480
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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