Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_08740Hypothetical protein. (325 aa)    
Predicted Functional Partners:
ISM_08735
Putative transporter, AEC family protein; COG0679 Predicted permeases.
       0.536
ISM_08725
S-formylglutathione hydrolase, putative; Serine hydrolase involved in the detoxification of formaldehyde.
       0.534
ISM_08750
Transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator.
       0.510
ISM_08745
Hypothetical protein.
       0.498
ISM_00990
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
    
 0.491
ISM_08730
Nitroreductase family protein; COG0778 Nitroreductase.
       0.490
ISM_08715
COG1671 Uncharacterized protein conserved in bacteria; Belongs to the UPF0178 family.
       0.482
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
     
 0.478
ISM_16010
Putative aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
   
 
  0.429
ISM_10631
COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
     
  0.422
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.