close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_08800NAD(P)H dehydrogenase, quinone family protein; COG2249 Putative NADPH-quinone reductase (modulator of drug activity B). (172 aa)    
Predicted Functional Partners:
ISM_17225
Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components.
  
 
 0.963
ISM_08795
Transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator.
 
     0.894
ISM_08015
COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).
  
  
  0.822
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
  0.702
ISM_12075
Decarboxylase, pyridoxal-dependent; COG0019 Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
  0.702
ISM_00255
Tryptophan repressor binding protein; COG0655 Multimeric flavodoxin WrbA.
    
 0.637
ISM_16925
Hypothetical protein; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.
   
 
 0.576
ISM_14290
COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases; Belongs to the complex I 20 kDa subunit family.
    
   0.493
ISM_04635
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
   
    0.403
ISM_10121
Aminotransferase, classes I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase.
   
    0.403
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (28%) [HD]