| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_00215 | ISM_05685 | ISM_00215 | ISM_05685 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | 0.991 |
| ISM_00215 | ISM_06925 | ISM_00215 | ISM_06925 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.996 |
| ISM_00215 | ISM_08960 | ISM_00215 | ISM_08960 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Ammonium transporter; COG0004 Ammonia permease. | 0.516 |
| ISM_00215 | ISM_09486 | ISM_00215 | ISM_09486 | Hypothetical protein; COG2199 FOG: GGDEF domain. | COG2200 FOG: EAL domain. | 0.996 |
| ISM_00215 | ISM_16640 | ISM_00215 | ISM_16640 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.437 |
| ISM_05410 | ISM_06100 | ISM_05410 | ISM_06100 | COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.598 |
| ISM_05410 | ISM_08960 | ISM_05410 | ISM_08960 | COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family. | Ammonium transporter; COG0004 Ammonia permease. | 0.995 |
| ISM_05410 | ISM_16640 | ISM_05410 | ISM_16640 | COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.968 |
| ISM_05410 | nadE | ISM_05410 | ISM_02210 | COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.515 |
| ISM_05685 | ISM_00215 | ISM_05685 | ISM_00215 | Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | Hypothetical protein; COG2199 FOG: GGDEF domain. | 0.991 |
| ISM_05685 | ISM_06925 | ISM_05685 | ISM_06925 | Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.995 |
| ISM_05685 | ISM_08960 | ISM_05685 | ISM_08960 | Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | Ammonium transporter; COG0004 Ammonia permease. | 0.664 |
| ISM_05685 | ISM_09486 | ISM_05685 | ISM_09486 | Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | COG2200 FOG: EAL domain. | 0.898 |
| ISM_05685 | ISM_16640 | ISM_05685 | ISM_16640 | Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.482 |
| ISM_06100 | ISM_05410 | ISM_06100 | ISM_05410 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family. | 0.598 |
| ISM_06100 | ISM_06925 | ISM_06100 | ISM_06925 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.478 |
| ISM_06100 | ISM_08960 | ISM_06100 | ISM_08960 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Ammonium transporter; COG0004 Ammonia permease. | 0.851 |
| ISM_06100 | ISM_08965 | ISM_06100 | ISM_08965 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG0347 Nitrogen regulatory protein PII. | 0.598 |
| ISM_06100 | ISM_16640 | ISM_06100 | ISM_16640 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.490 |
| ISM_06100 | nadE | ISM_06100 | ISM_02210 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.781 |