Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_09015COG2154 Pterin-4a-carbinolamine dehydratase. (101 aa)    
Predicted Functional Partners:
ISM_09010
COG3146 Uncharacterized protein conserved in bacteria.
  
    0.856
ISM_09000
Endoribonuclease L-PSP family protein; COG0251 Putative translation initiation inhibitor, yjgF family.
  
    0.808
ISM_09005
COG0584 Glycerophosphoryl diester phosphodiesterase.
       0.773
ISM_11525
methylmalonyl-CoA epimerase; COG0346 Lactoylglutathione lyase and related lyases.
  
  
 0.621
ISM_10201
Possible Histidine triad (HIT) protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.
   
   0.601
ISM_04130
Hypothetical protein; COG0657 Esterase/lipase.
    
   0.578
ISM_10016
Esterase, putative; COG0657 Esterase/lipase.
    
   0.578
ISM_05245
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 
 0.555
ISM_08755
COG1448 Aspartate/tyrosine/aromatic aminotransferase.
  
  
 0.533
ISM_09055
Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).
   
    0.406
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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