Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ISM_09070Hypothetical protein; COG3622 Hydroxypyruvate isomerase; Belongs to the hyi family. (258 aa)    
Predicted Functional Partners:
ISM_09065
COG3816 Uncharacterized protein conserved in bacteria.
       0.839
ISM_02775
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.
  
 
  0.778
ISM_03890
COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
 
 0.731
ISM_16580
6-phosphogluconate dehydrogenase domain protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
 
 0.682
ISM_09055
Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).
       0.639
ISM_09045
Hypothetical protein.
       0.632
ISM_09050
Hypothetical protein.
       0.630
ISM_08390
HpcH/HpaI aldolase family protein; COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
  
  
 0.586
ISM_09060
ATPase, MoxR family protein; COG0714 MoxR-like ATPases.
       0.585
ISM_03925
Probable oxidoreductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
 
 0.564
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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