STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_09165COG0515 Serine/threonine protein kinase. (349 aa)    
Predicted Functional Partners:
ISM_14700
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
  
 
 0.741
ISM_16740
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
  
 0.738
ISM_11860
Acetyltransferase, GNAT family protein; COG3153 Predicted acetyltransferase.
 
 
 0.674
ISM_16955
Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
 
 
 0.670
ISM_01395
Acetyltransferase, GNAT family protein; COG3153 Predicted acetyltransferase.
  
 
 0.627
ISM_14885
Xanthine dehydrogenase family protein, small/large subunits; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.
  
 
 0.607
ISM_03915
2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
  
 
 0.605
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
  
 0.596
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
  
 0.596
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
 
 0.595
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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