STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_09185Thiol-specific antioxidant protein; COG0450 Peroxiredoxin. (217 aa)    
Predicted Functional Partners:
ISM_08600
Thiol:disulfide interchange protein, putative; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 0.983
ISM_11325
Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 0.983
ISM_04820
Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 
 0.965
ISM_11070
COG0492 Thioredoxin reductase.
  
 
 0.947
ISM_00005
Hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.943
ISM_05370
AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.943
ISM_06815
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.769
ISM_07435
COG3118 Thioredoxin domain-containing protein.
  
 
 0.768
ISM_07130
Proteinase; COG0693 Putative intracellular protease/amidase.
   
 
 0.748
ISM_09180
COG1012 NAD-dependent aldehyde dehydrogenases.
   
 
 0.725
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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