STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_09311Hypothetical protein. (264 aa)    
Predicted Functional Partners:
ISM_09306
Membrane protein; COG0730 Predicted permeases.
       0.844
ISM_15245
Hypothetical protein; COG0466 ATP-dependent Lon protease, bacterial type.
  
     0.710
dddP
Metallopeptidase, family M24; Able to cleave dimethlysulfonioproprionate (DMSP), releasing dimethyl sulfide (DMS). DMS is the principal form by which sulfur is transported from oceans to the atmosphere. The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethlysulfonioproprionate lyase in vivo: the low activity with DMSP as substrate suggests that DMSP is not its native substrate.
  
     0.679
dusA
tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
       0.666
ISM_05960
Hypothetical protein.
  
     0.505
ISM_02175
Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein.
  
     0.499
ISM_15250
Rieske 2Fe-2S family protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.
  
     0.470
ISM_03455
Hypothetical protein; COG5457 Uncharacterized conserved small protein.
  
     0.457
ISM_11140
Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein.
  
     0.442
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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