nadK protein (Roseovarius nubinhibens) - STRING interaction network

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nadK

ATP-NAD kinase, putative; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (253 aa)

Predicted Functional Partners:

nadE

0.931

ISM_00270

0.928

nadD

0.911

pntA

0.891

ISM_08720

0.854

ISM_09431

0.850

ISM_14655

0.850

cobB

0.786

ISM_09586

0.769

ISM_06675

0.737

Your Current Organism:

Roseovarius nubinhibens

NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ISM_00270	ISM_06675	ISM_00270	ISM_06675	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	Phosphate acetyltransferase; COG0281 Malic enzyme.	0.422
ISM_00270	ISM_08720	ISM_00270	ISM_08720	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.	0.863
ISM_00270	ISM_09431	ISM_00270	ISM_09431	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	Hydrolase, NUDIX family protein; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.	0.850
ISM_00270	ISM_09586	ISM_00270	ISM_09586	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	Malate dehydrogenase; COG0281 Malic enzyme.	0.422
ISM_00270	ISM_14655	ISM_00270	ISM_14655	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	COG1694 Predicted pyrophosphatase.	0.853
ISM_00270	cobB	ISM_00270	ISM_01490	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.	0.741
ISM_00270	nadD	ISM_00270	ISM_05680	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.854
ISM_00270	nadE	ISM_00270	ISM_02210	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.902
ISM_00270	nadK	ISM_00270	ISM_09551	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	ATP-NAD kinase, putative; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.928
ISM_00270	pntA	ISM_00270	ISM_00275	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.	0.999
ISM_06675	ISM_00270	ISM_06675	ISM_00270	Phosphate acetyltransferase; COG0281 Malic enzyme.	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.422
ISM_06675	ISM_08720	ISM_06675	ISM_08720	Phosphate acetyltransferase; COG0281 Malic enzyme.	Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.	0.576
ISM_06675	ISM_09586	ISM_06675	ISM_09586	Phosphate acetyltransferase; COG0281 Malic enzyme.	Malate dehydrogenase; COG0281 Malic enzyme.	0.786
ISM_06675	cobB	ISM_06675	ISM_01490	Phosphate acetyltransferase; COG0281 Malic enzyme.	COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.	0.446
ISM_06675	nadE	ISM_06675	ISM_02210	Phosphate acetyltransferase; COG0281 Malic enzyme.	NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.697
ISM_06675	nadK	ISM_06675	ISM_09551	Phosphate acetyltransferase; COG0281 Malic enzyme.	ATP-NAD kinase, putative; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.737
ISM_06675	pntA	ISM_06675	ISM_00275	Phosphate acetyltransferase; COG0281 Malic enzyme.	NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.	0.538
ISM_08720	ISM_00270	ISM_08720	ISM_00270	Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.	NAD(P)+ transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.863
ISM_08720	ISM_06675	ISM_08720	ISM_06675	Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.	Phosphate acetyltransferase; COG0281 Malic enzyme.	0.576
ISM_08720	ISM_09431	ISM_08720	ISM_09431	Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.	Hydrolase, NUDIX family protein; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.	0.850

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