| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_01185 | ISM_01450 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | COG2086 Electron transfer flavoprotein, beta subunit. | 0.875 |
| ISM_01185 | ISM_01455 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | COG2025 Electron transfer flavoprotein, alpha subunit. | 0.925 |
| ISM_01185 | ISM_02040 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | COG1960 Acyl-CoA dehydrogenases. | 0.936 |
| ISM_01185 | ISM_02060 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.661 |
| ISM_01185 | ISM_02075 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | AMP-binding protein; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. | 0.409 |
| ISM_01185 | ISM_04125 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.661 |
| ISM_01185 | ISM_09776 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | COG1960 Acyl-CoA dehydrogenases. | 0.936 |
| ISM_01185 | ISM_16740 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.968 |
| ISM_01450 | ISM_01185 | COG2086 Electron transfer flavoprotein, beta subunit. | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | 0.875 |
| ISM_01450 | ISM_01455 | COG2086 Electron transfer flavoprotein, beta subunit. | COG2025 Electron transfer flavoprotein, alpha subunit. | 0.999 |
| ISM_01450 | ISM_02040 | COG2086 Electron transfer flavoprotein, beta subunit. | COG1960 Acyl-CoA dehydrogenases. | 0.857 |
| ISM_01450 | ISM_02060 | COG2086 Electron transfer flavoprotein, beta subunit. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.875 |
| ISM_01450 | ISM_04125 | COG2086 Electron transfer flavoprotein, beta subunit. | 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.875 |
| ISM_01450 | ISM_09776 | COG2086 Electron transfer flavoprotein, beta subunit. | COG1960 Acyl-CoA dehydrogenases. | 0.879 |
| ISM_01455 | ISM_01185 | COG2025 Electron transfer flavoprotein, alpha subunit. | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | 0.925 |
| ISM_01455 | ISM_01450 | COG2025 Electron transfer flavoprotein, alpha subunit. | COG2086 Electron transfer flavoprotein, beta subunit. | 0.999 |
| ISM_01455 | ISM_02040 | COG2025 Electron transfer flavoprotein, alpha subunit. | COG1960 Acyl-CoA dehydrogenases. | 0.885 |
| ISM_01455 | ISM_02060 | COG2025 Electron transfer flavoprotein, alpha subunit. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.925 |
| ISM_01455 | ISM_04125 | COG2025 Electron transfer flavoprotein, alpha subunit. | 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.925 |
| ISM_01455 | ISM_05820 | COG2025 Electron transfer flavoprotein, alpha subunit. | COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.545 |