Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_09996Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component. (395 aa)    
Predicted Functional Partners:
glnD
protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
       0.820
rsmI
Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
   0.728
ISM_02275
Hypothetical protein; COG1466 DNA polymerase III, delta subunit.
  
     0.690
ISM_10006
Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.
       0.659
ISM_15175
COG1426 Uncharacterized protein conserved in bacteria.
  
     0.656
ISM_05440
COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.
  
 
 0.649
ISM_05475
COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.
  
 
 0.649
ISM_05890
COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.
  
 
 0.649
ISM_05920
Hypothetical protein; COG0419 ATPase involved in DNA repair.
  
     0.605
ISM_16365
Lipoprotein, SmpA/OmlA family protein; COG2913 Small protein A (tmRNA-binding).
  
     0.598
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.