Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_10036K+-dependent Na+/Ca+ exchanger related-protein; COG0530 Ca2+/Na+ antiporter. (318 aa)    
Predicted Functional Partners:
ISM_10026
Peptidase, family S49; COG0616 Periplasmic serine proteases (ClpP class).
       0.845
ISM_10031
Hypothetical protein.
       0.844
ISM_10041
Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
       0.720
ISM_12210
Putative Na+/H+ antiporter with cyclic nucleotide-binding domain; COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.
   
 
 0.624
ISM_01965
Oxidoreductase, short-chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
   0.602
ISM_05235
Probable oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
   0.602
ISM_16435
Sodium/hydrogen exchanger; COG0025 NhaP-type Na+/H+ and K+/H+ antiporters.
 
 
 
 0.587
ISM_10021
Competence protein ComM; COG0606 Predicted ATPase with chaperone activity.
       0.549
ISM_04860
WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat.
   
   0.543
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
    0.528
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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