Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_10161Anti-sigma B factor, putative; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). (155 aa)    
Predicted Functional Partners:
ISM_10166
COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
 0.999
ISM_06625
Response regulator; COG0784 FOG: CheY-like receiver.
 
 0.995
ISM_12045
Hypothetical protein.
  
    0.989
ISM_06630
COG2198 FOG: HPt domain.
 
 
 0.986
ISM_11350
COG1536 Flagellar motor switch protein.
   
    0.962
ISM_17360
TraF protein; COG0840 Methyl-accepting chemotaxis protein.
  
    0.893
ISM_05265
Diguanylate cyclase, putative; COG2200 FOG: EAL domain.
  
 
 0.892
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
  
 0.836
ISM_12050
Diguanylate cyclase, putative; COG2199 FOG: GGDEF domain.
  
 
 0.832
ISM_15080
Hypothetical protein; COG2963 Transposase and inactivated derivatives.
   
  
 0.769
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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