Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ISM_10256COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. (509 aa)    
Predicted Functional Partners:
ISM_13450
Corrinoid methyltransferase protein, putative; COG5012 Predicted cobalamin binding protein.
 
 
  0.916
ISM_10266
Dimethylglycine dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.
 
     0.829
ISM_10261
Putative oxidoreductase protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.
 
     0.816
ISM_16340
COG3894 Uncharacterized metal-binding protein.
 
     0.779
ISM_13445
Hypothetical protein.
 
     0.777
ISM_15125
Hypothetical protein.
 
     0.776
ISM_10271
Putative aminotransferase protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.773
ISM_15115
Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain.
 
     0.758
ISM_13465
Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
  
     0.668
ISM_08155
Flavin-containing monooxygenase; COG2072 Predicted flavoprotein involved in K+ transport.
     
  0.595
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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