| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_10251 | ISM_10256 | COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.540 |
| ISM_10251 | ISM_10261 | COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Putative oxidoreductase protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.540 |
| ISM_10251 | ISM_10266 | COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Dimethylglycine dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.540 |
| ISM_10251 | ISM_10271 | COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Putative aminotransferase protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.540 |
| ISM_10256 | ISM_10251 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.540 |
| ISM_10256 | ISM_10261 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Putative oxidoreductase protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.816 |
| ISM_10256 | ISM_10266 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Dimethylglycine dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.830 |
| ISM_10256 | ISM_10271 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Putative aminotransferase protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.773 |
| ISM_10256 | ISM_13445 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein. | 0.776 |
| ISM_10256 | ISM_13450 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Corrinoid methyltransferase protein, putative; COG5012 Predicted cobalamin binding protein. | 0.824 |
| ISM_10256 | ISM_13465 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.668 |
| ISM_10256 | ISM_15115 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | 0.756 |
| ISM_10256 | ISM_15125 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein. | 0.774 |
| ISM_10256 | ISM_16340 | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | COG3894 Uncharacterized metal-binding protein. | 0.778 |
| ISM_10261 | ISM_10251 | Putative oxidoreductase protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.540 |
| ISM_10261 | ISM_10256 | Putative oxidoreductase protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.816 |
| ISM_10261 | ISM_10266 | Putative oxidoreductase protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Dimethylglycine dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.966 |
| ISM_10261 | ISM_10271 | Putative oxidoreductase protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Putative aminotransferase protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.914 |
| ISM_10261 | ISM_13465 | Putative oxidoreductase protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.576 |
| ISM_10261 | ISM_15115 | Putative oxidoreductase protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | 0.509 |