Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_10371Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. (488 aa)    
Predicted Functional Partners:
pyrB
COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 0.982
ISM_13635
COG0167 Dihydroorotate dehydrogenase.
 
 0.969
ISM_13620
N-carbamoyl-L-amino acid amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.
 
 
 0.929
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.864
ISM_10326
Hypothetical protein; COG4126 Hydantoin racemase.
 
  
  0.858
ISM_01980
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.851
carA
COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
 
  
 0.819
carB
COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
 
 
 0.804
ISM_10341
N-carbamyl-D-amino acid amidohydrolase; COG0388 Predicted amidohydrolase.
 
 
  0.794
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.792
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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