Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
msrA-3Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (156 aa)    
Predicted Functional Partners:
msrB
Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.
 
 0.993
ISM_00350
Hypothetical protein; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.
 
 0.952
ISM_08600
Thiol:disulfide interchange protein, putative; COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.728
ISM_11325
Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.728
ISM_10381
COG0526 Thiol-disulfide isomerase and thioredoxins.
 
  
 0.666
ISM_06560
Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
 
 0.628
ISM_11635
COG0695 Glutaredoxin and related proteins.
  
 
 0.628
ISM_17360
TraF protein; COG0840 Methyl-accepting chemotaxis protein.
    
   0.539
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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