STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrA-3Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (156 aa)    
Predicted Functional Partners:
msrB
Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.
 
 0.994
ISM_00350
Hypothetical protein; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.
 
 0.962
ISM_08600
Thiol:disulfide interchange protein, putative; COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.959
ISM_11325
Periplasmic protein thiol:disulfide oxidoreductase, DsbE subfamily protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
   
 0.959
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.846
ISM_06560
Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
 
 0.706
ISM_11635
COG0695 Glutaredoxin and related proteins.
  
 
 0.706
ISM_10381
COG0526 Thiol-disulfide isomerase and thioredoxins.
 
   
 0.659
ISM_17360
TraF protein; COG0840 Methyl-accepting chemotaxis protein.
    
   0.632
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.