Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_10526COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa)    
Predicted Functional Partners:
ISM_10531
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
 
 0.997
gpmI
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.857
ISM_10536
COG0560 Phosphoserine phosphatase.
 
 0.798
ISM_00490
COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family.
    
 0.777
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 
 0.755
ISM_15140
Phosphoglycerate mutase family protein; COG0406 Fructose-2,6-bisphosphatase.
  
 
 0.747
ISM_08755
COG1448 Aspartate/tyrosine/aromatic aminotransferase.
   
 0.742
ISM_15265
COG0440 Acetolactate synthase, small (regulatory) subunit.
 
 
 0.685
ISM_04635
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
 0.679
ISM_13135
COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
 0.679
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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