| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_02775 | ISM_03095 | ISM_02775 | ISM_03095 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | COG0498 Threonine synthase. | 0.436 |
| ISM_02775 | ISM_07820 | ISM_02775 | ISM_07820 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | COG0031 Cysteine synthase. | 0.471 |
| ISM_02775 | ISM_10526 | ISM_02775 | ISM_10526 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.492 |
| ISM_02775 | ISM_10531 | ISM_02775 | ISM_10531 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.907 |
| ISM_02775 | ISM_10536 | ISM_02775 | ISM_10536 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | COG0560 Phosphoserine phosphatase. | 0.526 |
| ISM_02775 | ISM_12190 | ISM_02775 | ISM_12190 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | COG0031 Cysteine synthase. | 0.471 |
| ISM_02775 | ISM_12455 | ISM_02775 | ISM_12455 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.741 |
| ISM_03095 | ISM_02775 | ISM_03095 | ISM_02775 | COG0498 Threonine synthase. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | 0.436 |
| ISM_03095 | ISM_07820 | ISM_03095 | ISM_07820 | COG0498 Threonine synthase. | COG0031 Cysteine synthase. | 0.501 |
| ISM_03095 | ISM_09441 | ISM_03095 | ISM_09441 | COG0498 Threonine synthase. | COG0077 Prephenate dehydratase. | 0.402 |
| ISM_03095 | ISM_10526 | ISM_03095 | ISM_10526 | COG0498 Threonine synthase. | COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.468 |
| ISM_03095 | ISM_10531 | ISM_03095 | ISM_10531 | COG0498 Threonine synthase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.953 |
| ISM_03095 | ISM_10536 | ISM_03095 | ISM_10536 | COG0498 Threonine synthase. | COG0560 Phosphoserine phosphatase. | 0.691 |
| ISM_03095 | ISM_12190 | ISM_03095 | ISM_12190 | COG0498 Threonine synthase. | COG0031 Cysteine synthase. | 0.501 |
| ISM_03095 | pdxA | ISM_03095 | ISM_17145 | COG0498 Threonine synthase. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.855 |
| ISM_07820 | ISM_02775 | ISM_07820 | ISM_02775 | COG0031 Cysteine synthase. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. | 0.471 |
| ISM_07820 | ISM_03095 | ISM_07820 | ISM_03095 | COG0031 Cysteine synthase. | COG0498 Threonine synthase. | 0.501 |
| ISM_07820 | ISM_10526 | ISM_07820 | ISM_10526 | COG0031 Cysteine synthase. | COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.482 |
| ISM_07820 | ISM_10531 | ISM_07820 | ISM_10531 | COG0031 Cysteine synthase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.669 |
| ISM_07820 | ISM_10536 | ISM_07820 | ISM_10536 | COG0031 Cysteine synthase. | COG0560 Phosphoserine phosphatase. | 0.484 |
