| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_00300 | ISM_04820 | COG0308 Aminopeptidase N. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.557 |
| ISM_00300 | ISM_10551 | COG0308 Aminopeptidase N. | N-methylproline demethylase, putative; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.402 |
| ISM_01450 | ISM_01455 | COG2086 Electron transfer flavoprotein, beta subunit. | COG2025 Electron transfer flavoprotein, alpha subunit. | 0.999 |
| ISM_01450 | ISM_04820 | COG2086 Electron transfer flavoprotein, beta subunit. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.750 |
| ISM_01450 | ISM_10551 | COG2086 Electron transfer flavoprotein, beta subunit. | N-methylproline demethylase, putative; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.696 |
| ISM_01455 | ISM_01450 | COG2025 Electron transfer flavoprotein, alpha subunit. | COG2086 Electron transfer flavoprotein, beta subunit. | 0.999 |
| ISM_01455 | ISM_04820 | COG2025 Electron transfer flavoprotein, alpha subunit. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.789 |
| ISM_01455 | ISM_10551 | COG2025 Electron transfer flavoprotein, alpha subunit. | N-methylproline demethylase, putative; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.623 |
| ISM_04820 | ISM_00300 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG0308 Aminopeptidase N. | 0.557 |
| ISM_04820 | ISM_01450 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG2086 Electron transfer flavoprotein, beta subunit. | 0.750 |
| ISM_04820 | ISM_01455 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG2025 Electron transfer flavoprotein, alpha subunit. | 0.789 |
| ISM_04820 | ISM_06100 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.958 |
| ISM_04820 | ISM_06305 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Oxygen-insensitive NAD(P)H nitroreductase; COG0778 Nitroreductase. | 0.469 |
| ISM_04820 | ISM_08730 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Nitroreductase family protein; COG0778 Nitroreductase. | 0.469 |
| ISM_04820 | ISM_10551 | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | N-methylproline demethylase, putative; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.456 |
| ISM_06100 | ISM_04820 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.958 |
| ISM_06100 | ISM_10551 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | N-methylproline demethylase, putative; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.652 |
| ISM_06305 | ISM_04820 | Oxygen-insensitive NAD(P)H nitroreductase; COG0778 Nitroreductase. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.469 |
| ISM_06305 | ISM_08730 | Oxygen-insensitive NAD(P)H nitroreductase; COG0778 Nitroreductase. | Nitroreductase family protein; COG0778 Nitroreductase. | 0.556 |
| ISM_06305 | ISM_10551 | Oxygen-insensitive NAD(P)H nitroreductase; COG0778 Nitroreductase. | N-methylproline demethylase, putative; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.475 |