Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ISM_10576Hypothetical protein; COG0510 Predicted choline kinase involved in LPS biosynthesis. (287 aa)    
Predicted Functional Partners:
ISM_10571
Sarcosine dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.
 
     0.934
ISM_10581
COG1349 Transcriptional regulators of sugar metabolism.
 
     0.731
ISM_03030
Hypothetical protein; COG0170 Dolichol kinase.
    
 
 0.682
ISM_10566
Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.
 
     0.629
ISM_00955
Putative permease transmembrane protein; COG0531 Amino acid transporters.
  
   0.597
ISM_01540
Phospholipase D/Transphosphatidylase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.
   
 
 0.541
ISM_15360
COG0531 Amino acid transporters.
  
   0.537
ISM_10651
COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
     
 0.486
ISM_14495
Glycine betaine/proline ABC transporter, periplasmic substrate-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.
 
     0.474
ISM_10641
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
     
 0.440
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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