| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_02665 | ISM_10426 | ISM_02665 | ISM_10426 | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | COG3258 Cytochrome c. | 0.991 |
| ISM_02665 | ISM_10456 | ISM_02665 | ISM_10456 | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | COG2010 Cytochrome c, mono- and diheme variants. | 0.980 |
| ISM_02665 | ISM_10700 | ISM_02665 | ISM_10700 | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.917 |
| ISM_04870 | ISM_04900 | ISM_04870 | ISM_04900 | Formate dehydrogenase, iron-sulfur subunit, putative; COG0437 Fe-S-cluster-containing hydrogenase components 1. | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | 0.965 |
| ISM_04870 | ISM_08760 | ISM_04870 | ISM_08760 | Formate dehydrogenase, iron-sulfur subunit, putative; COG0437 Fe-S-cluster-containing hydrogenase components 1. | Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase. | 0.658 |
| ISM_04870 | ISM_10426 | ISM_04870 | ISM_10426 | Formate dehydrogenase, iron-sulfur subunit, putative; COG0437 Fe-S-cluster-containing hydrogenase components 1. | COG3258 Cytochrome c. | 0.955 |
| ISM_04870 | ISM_10456 | ISM_04870 | ISM_10456 | Formate dehydrogenase, iron-sulfur subunit, putative; COG0437 Fe-S-cluster-containing hydrogenase components 1. | COG2010 Cytochrome c, mono- and diheme variants. | 0.960 |
| ISM_04870 | ISM_10700 | ISM_04870 | ISM_10700 | Formate dehydrogenase, iron-sulfur subunit, putative; COG0437 Fe-S-cluster-containing hydrogenase components 1. | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.992 |
| ISM_04870 | ISM_10710 | ISM_04870 | ISM_10710 | Formate dehydrogenase, iron-sulfur subunit, putative; COG0437 Fe-S-cluster-containing hydrogenase components 1. | Dimethyl sulfoxide reductase, C subunit, putative; COG3302 DMSO reductase anchor subunit. | 0.774 |
| ISM_04870 | ISM_15735 | ISM_04870 | ISM_15735 | Formate dehydrogenase, iron-sulfur subunit, putative; COG0437 Fe-S-cluster-containing hydrogenase components 1. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.645 |
| ISM_04870 | cysC | ISM_04870 | ISM_11065 | Formate dehydrogenase, iron-sulfur subunit, putative; COG0437 Fe-S-cluster-containing hydrogenase components 1. | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.826 |
| ISM_04900 | ISM_04870 | ISM_04900 | ISM_04870 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Formate dehydrogenase, iron-sulfur subunit, putative; COG0437 Fe-S-cluster-containing hydrogenase components 1. | 0.965 |
| ISM_04900 | ISM_10700 | ISM_04900 | ISM_10700 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.946 |
| ISM_04900 | ISM_10705 | ISM_04900 | ISM_10705 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Iron-sulfur cluster-binding protein; COG0437 Fe-S-cluster-containing hydrogenase components 1. | 0.832 |
| ISM_04900 | ISM_10710 | ISM_04900 | ISM_10710 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Dimethyl sulfoxide reductase, C subunit, putative; COG3302 DMSO reductase anchor subunit. | 0.540 |
| ISM_04900 | cysC | ISM_04900 | ISM_11065 | Iron-sulfur cluster-binding protein; COG1145 Ferredoxin. | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.428 |
| ISM_08760 | ISM_04870 | ISM_08760 | ISM_04870 | Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase. | Formate dehydrogenase, iron-sulfur subunit, putative; COG0437 Fe-S-cluster-containing hydrogenase components 1. | 0.658 |
| ISM_08760 | ISM_10426 | ISM_08760 | ISM_10426 | Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase. | COG3258 Cytochrome c. | 0.953 |
| ISM_08760 | ISM_10456 | ISM_08760 | ISM_10456 | Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase. | COG2010 Cytochrome c, mono- and diheme variants. | 0.943 |
| ISM_08760 | ISM_10700 | ISM_08760 | ISM_10700 | Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase. | Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.920 |