Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_10705Iron-sulfur cluster-binding protein; COG0437 Fe-S-cluster-containing hydrogenase components 1. (264 aa)    
Predicted Functional Partners:
ISM_10700
Oxidoreductase, molybdopterin-binding; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 0.998
ISM_10710
Dimethyl sulfoxide reductase, C subunit, putative; COG3302 DMSO reductase anchor subunit.
 
 
 0.995
ISM_04865
COG2864 Cytochrome b subunit of formate dehydrogenase.
  
 0.975
ISM_02905
Molybdopterin oxidoreductase:Molydopterin dinucleotide-bindingregion; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 0.927
cysC
Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate.
     
 0.909
ISM_10426
COG3258 Cytochrome c.
   
 0.902
ISM_10456
COG2010 Cytochrome c, mono- and diheme variants.
  
 0.885
ISM_04875
Putative formate dehydrogenase large subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.863
ISM_08760
Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase.
     
 0.859
ISM_05365
Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
   
 0.856
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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