Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pcaHCOG3485 Protocatechuate 3,4-dioxygenase beta subunit. (242 aa)    
Predicted Functional Partners:
ISM_10940
COG3485 Protocatechuate 3,4-dioxygenase beta subunit.
 
0.999
ISM_10960
4-hydroxybenzoate 3-monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
 
  
 0.993
pcaC
4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
 
 
 0.983
ISM_10955
3-oxoadipate enol-lactone hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
  
 0.957
ISM_06220
COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 
 0.917
ISM_10965
Pca operon transcriptional activator PcaQ; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
     0.818
ISM_10935
Hypothetical protein.
 
   
 0.800
ISM_12060
COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
 
 
 0.752
ISM_00815
3-oxoadipate enol-lactone hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
  
 0.723
ISM_03160
COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit.
  
 
 0.598
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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