Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pcaC4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. (136 aa)    
Predicted Functional Partners:
ISM_10955
3-oxoadipate enol-lactone hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
 0.997
ISM_00815
3-oxoadipate enol-lactone hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
 0.984
pcaH
COG3485 Protocatechuate 3,4-dioxygenase beta subunit.
 
 
 0.983
ISM_10940
COG3485 Protocatechuate 3,4-dioxygenase beta subunit.
 
 
 0.982
ISM_10960
4-hydroxybenzoate 3-monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
 
   
 0.975
ISM_04270
3-oxoadipate enol-lactonase family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
 0.940
ISM_06220
COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 
 0.917
ISM_10935
Hypothetical protein.
    
  0.819
ISM_12060
COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
  
  
 
0.778
ISM_14370
4-carboxymuconolactone decarboxylase, putative; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
  
  
  0.774
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (18%) [HD]