| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_09215 | ISM_11000 | ISM_09215 | ISM_11000 | Glycosyl hydrolase, BNR repeat protein; COG4692 Predicted neuraminidase (sialidase). | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | 0.425 |
| ISM_10990 | ISM_11000 | ISM_10990 | ISM_11000 | Na/Pi-cotransporter family protein; COG1283 Na+/phosphate symporter. | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | 0.503 |
| ISM_11000 | ISM_09215 | ISM_11000 | ISM_09215 | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | Glycosyl hydrolase, BNR repeat protein; COG4692 Predicted neuraminidase (sialidase). | 0.425 |
| ISM_11000 | ISM_10990 | ISM_11000 | ISM_10990 | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | Na/Pi-cotransporter family protein; COG1283 Na+/phosphate symporter. | 0.503 |
| ISM_11000 | ISM_11005 | ISM_11000 | ISM_11005 | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component. | 0.468 |
| ISM_11000 | ISM_16555 | ISM_11000 | ISM_16555 | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | Putative oxidoreductase protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.412 |
| ISM_11000 | rpoA | ISM_11000 | ISM_01675 | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.529 |
| ISM_11000 | rpoB | ISM_11000 | ISM_01895 | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.543 |
| ISM_11000 | rpoZ | ISM_11000 | ISM_13780 | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.567 |
| ISM_11005 | ISM_11000 | ISM_11005 | ISM_11000 | Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component. | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | 0.468 |
| ISM_16555 | ISM_11000 | ISM_16555 | ISM_11000 | Putative oxidoreductase protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | 0.412 |
| rpoA | ISM_11000 | ISM_01675 | ISM_11000 | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | 0.529 |
| rpoA | rpoB | ISM_01675 | ISM_01895 | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.998 |
| rpoA | rpoZ | ISM_01675 | ISM_13780 | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.995 |
| rpoB | ISM_11000 | ISM_01895 | ISM_11000 | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | 0.543 |
| rpoB | rpoA | ISM_01895 | ISM_01675 | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.998 |
| rpoB | rpoZ | ISM_01895 | ISM_13780 | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.986 |
| rpoZ | ISM_11000 | ISM_13780 | ISM_11000 | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | Phosphonate monoester hydrolase, putative; COG3119 Arylsulfatase A and related enzymes. | 0.567 |
| rpoZ | rpoA | ISM_13780 | ISM_01675 | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.995 |
| rpoZ | rpoB | ISM_13780 | ISM_01895 | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.986 |