Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISM_11115Hypothetical protein. (155 aa)    
Predicted Functional Partners:
ISM_11125
Chaperonin csaA; COG0073 EMAP domain.
       0.807
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.755
ISM_00345
DnaJ domain protein; COG2214 DnaJ-class molecular chaperone.
  
     0.742
ISM_11130
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.737
ISM_06785
Transporter, Tim44 family protein; COG4395 Uncharacterized protein conserved in bacteria.
  
     0.704
ISM_17110
COG2927 DNA polymerase III, chi subunit.
  
     0.694
secE
Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
     0.670
ISM_01175
COG3750 Uncharacterized protein conserved in bacteria.
  
     0.647
ISM_12425
COG3814 Uncharacterized protein conserved in bacteria.
  
     0.610
ISM_11580
Hypothetical protein.
  
     0.608
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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