| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_03325 | ISM_03330 | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | 0.999 |
| ISM_03325 | ISM_11365 | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | COG1414 Transcriptional regulator. | 0.615 |
| ISM_03325 | ISM_11370 | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | COG1414 Transcriptional regulator. | 0.615 |
| ISM_03325 | ISM_11405 | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | Possible gamma-glutamyltranspeptidase precursor; COG0405 Gamma-glutamyltransferase. | 0.529 |
| ISM_03330 | ISM_03325 | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | 0.999 |
| ISM_03330 | ISM_11365 | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | COG1414 Transcriptional regulator. | 0.637 |
| ISM_03330 | ISM_11370 | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | COG1414 Transcriptional regulator. | 0.637 |
| ISM_03330 | ISM_11405 | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | Possible gamma-glutamyltranspeptidase precursor; COG0405 Gamma-glutamyltransferase. | 0.569 |
| ISM_03915 | ISM_11365 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | COG1414 Transcriptional regulator. | 0.493 |
| ISM_03915 | ISM_11370 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | COG1414 Transcriptional regulator. | 0.560 |
| ISM_03915 | ISM_14700 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.761 |
| ISM_03915 | ISM_16955 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.997 |
| ISM_11365 | ISM_03325 | COG1414 Transcriptional regulator. | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | 0.615 |
| ISM_11365 | ISM_03330 | COG1414 Transcriptional regulator. | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | 0.637 |
| ISM_11365 | ISM_03915 | COG1414 Transcriptional regulator. | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.493 |
| ISM_11365 | ISM_11370 | COG1414 Transcriptional regulator. | COG1414 Transcriptional regulator. | 0.929 |
| ISM_11365 | ISM_11375 | COG1414 Transcriptional regulator. | COG0747 ABC-type dipeptide transport system, periplasmic component. | 0.861 |
| ISM_11365 | ISM_11380 | COG1414 Transcriptional regulator. | COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components. | 0.595 |
| ISM_11365 | ISM_11405 | COG1414 Transcriptional regulator. | Possible gamma-glutamyltranspeptidase precursor; COG0405 Gamma-glutamyltransferase. | 0.706 |
| ISM_11365 | ISM_11410 | COG1414 Transcriptional regulator. | Peptidase M20; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | 0.713 |
