Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tadACytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (151 aa)    
Predicted Functional Partners:
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolaseII, putative; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.845
hisE
COG0140 Phosphoribosyl-ATP pyrophosphohydrolase.
   
  
 0.837
ISM_14885
Xanthine dehydrogenase family protein, small/large subunits; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.
    
 0.770
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
 0.740
ISM_13635
COG0167 Dihydroorotate dehydrogenase.
    
  0.731
ISM_11230
COG0402 Cytosine deaminase and related metal-dependent hydrolases.
    
 0.720
ISM_00820
Oxidoreductase, zinc-binding dehydrogenase family protein; COG1062 Zn-dependent alcohol dehydrogenases, class III.
  
 
  0.705
ISM_02320
Glutathione-dependent formaldehyde dehydrogenase; COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 
  0.705
ISM_11490
COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.
       0.693
ISM_11085
Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.646
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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