STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gloBPutative hydroxyacylglutathione hydrolase (glyoxalase II) (GLX II)protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (255 aa)    
Predicted Functional Partners:
ISM_13160
Lactoylglutathione lyase, putative; COG0346 Lactoylglutathione lyase and related lyases.
 
 0.959
ISM_06365
COG0346 Lactoylglutathione lyase and related lyases.
  
 0.938
ISM_00405
Putative D-lactate dehydrogenase (cytochrome), FAD/FMN-containingoxidoreductase; COG0277 FAD/FMN-containing dehydrogenases.
     
 0.850
ISM_10720
Hypothetical protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
  
 0.820
ISM_11710
Hypothetical protein; COG0500 SAM-dependent methyltransferases.
     
 0.707
gshB
COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.
 
   
 0.614
ISM_11700
ATP-dependent Clp protease, ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.
     
 0.612
ybeY
Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
 
 
 
 0.597
ISM_11695
Peptidase, M23/M37 family protein; COG0739 Membrane proteins related to metalloendopeptidases.
       0.579
ISM_14440
Hypothetical protein; COG0607 Rhodanese-related sulfurtransferase.
  
 0.575
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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