Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_11710Hypothetical protein; COG0500 SAM-dependent methyltransferases. (246 aa)    
Predicted Functional Partners:
ISM_16740
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
    
 0.767
gloB
Putative hydroxyacylglutathione hydrolase (glyoxalase II) (GLX II)protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
     
 0.707
ISM_04765
HemY domain protein; COG3071 Uncharacterized enzyme of heme biosynthesis.
  
     0.700
ISM_09526
Decaprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.698
ISM_15535
Farnesyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.698
ISM_04575
Hypothetical protein; COG1562 Phytoene/squalene synthetase.
 
  
 0.685
ISM_02105
DNA-binding protein, putative; COG1396 Predicted transcriptional regulators.
  
     0.664
ISM_11810
HAD-superfamily subfamily IIA hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.
 
  
  0.652
ISM_01290
COG4765 Uncharacterized protein conserved in bacteria.
  
     0.642
ISM_06870
HD domain protein; COG1896 Predicted hydrolases of HD superfamily.
  
     0.608
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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