Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
ISM_11775Transcriptional regulator, GntR family protein; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs. (497 aa)    
Predicted Functional Partners:
ISM_11780
Hypothetical protein; COG3467 Predicted flavin-nucleotide-binding protein.
 
    0.822
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
     
  0.714
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.665
ISM_04900
Iron-sulfur cluster-binding protein; COG1145 Ferredoxin.
    
   0.558
ISM_04010
Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases.
    
  0.556
ISM_16740
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
     
 0.475
ISM_04300
Putative aminomethyltransferase protein; Belongs to the GcvT family.
   
 
  0.470
ISM_15390
Putative aminomethyltransferase protein; Belongs to the GcvT family.
   
 
  0.470
ISM_10271
Putative aminotransferase protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.460
ISM_11935
Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins.
  
   
 0.414
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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