Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lysSCOG1384 Lysyl-tRNA synthetase (class I); Belongs to the class-I aminoacyl-tRNA synthetase family. (547 aa)    
Predicted Functional Partners:
ISM_12070
COG3820 Uncharacterized protein conserved in bacteria.
  
    0.777
ISM_11830
Hypothetical protein.
       0.699
ISM_12425
COG3814 Uncharacterized protein conserved in bacteria.
  
     0.697
ISM_06785
Transporter, Tim44 family protein; COG4395 Uncharacterized protein conserved in bacteria.
  
     0.641
ISM_11825
FAD dependent oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases.
       0.551
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
     0.544
nusG
Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.
   
    0.523
ISM_02105
DNA-binding protein, putative; COG1396 Predicted transcriptional regulators.
  
     0.520
ISM_00380
Cobalt chelatase, pCobT subunit; COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
     0.518
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
    0.518
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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