Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_11845COG1652 Uncharacterized protein containing LysM domain. (131 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.627
ISM_05190
COG5281 Phage-related minor tail protein.
   
   0.588
ISM_12820
Phage-related protein, probable phage tail tape meausure protein, lambda family protein; COG0840 Methyl-accepting chemotaxis protein.
   
   0.588
ISM_00255
Tryptophan repressor binding protein; COG0655 Multimeric flavodoxin WrbA.
   
  
 0.586
ISM_11840
Hypothetical protein.
       0.511
ISM_02345
NLP/P60 family protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).
   
 
 0.495
ISM_05205
Hypothetical protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).
   
 
 0.495
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
  
  
  0.449
ISM_13850
Hypothetical protein; COG0655 Multimeric flavodoxin WrbA.
   
    0.437
ISM_15450
COG1957 Inosine-uridine nucleoside N-ribohydrolase.
  
  
  0.437
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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