Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ISM_11860Acetyltransferase, GNAT family protein; COG3153 Predicted acetyltransferase. (161 aa)    
Predicted Functional Partners:
ISM_11865
Hypothetical protein; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.
       0.819
ISM_09165
COG0515 Serine/threonine protein kinase.
 
 
 0.674
ISM_11870
Lipoprotein, putative.
       0.668
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
    
  0.648
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.627
ISM_04095
Benzoate-coenzyme A ligase; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
  
 
 0.627
ISM_09576
propionate--CoA ligase; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
  
 
 0.627
ISM_14240
COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
  
 
 0.627
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
     
  0.617
ISM_11855
Hypothetical protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
       0.491
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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