Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
ISM_11905Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. (302 aa)    
Predicted Functional Partners:
ISM_11895
TRAP dicarboxylate transporter, DctM subunit; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.
  
    0.775
ISM_11890
Putative small integral membrane tranport protein; COG4665 TRAP-type mannitol/chloroaromatic compound transport system, small permease component.
       0.773
ISM_11900
Carboxyvinyl-carboxyphosphonate phosphorylmutase; COG2513 PEP phosphonomutase and related enzymes.
       0.773
ISM_11885
C4-dicarboxylate-binding periplasmic protein precursor; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.
       0.532
ISM_16450
Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.
  
     0.426
secY
Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
   0.423
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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