STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_11935Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins. (281 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.889
ISM_11145
Transcriptional regulator, AraC family protein; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
  
   0.758
ISM_03655
Transcriptional regulator, AraC family protein; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
  
   0.756
ISM_11930
Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.
 
     0.740
ISM_07520
COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
  
   0.708
ISM_11485
Transcriptional regulator, AraC family protein; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
  
   0.708
ISM_09095
Transcriptional regulator, AraC family protein; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
  
   0.633
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
    
  0.602
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.600
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.596
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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