Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ISM_12150Hypothetical protein. (65 aa)    
Predicted Functional Partners:
ISM_12140
HflK protein; HflC and HflK could encode or regulate a protease.
     
 0.845
ISM_12145
HflC protein; HflC and HflK could regulate a protease.
     
 0.845
ISM_12135
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
       0.693
ISM_09826
Peptidoglycan binding domain protein; COG2951 Membrane-bound lytic murein transglycosylase B.
 
     0.595
ISM_14730
Hypothetical protein.
  
     0.595
nnrD
YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
     
 0.589
ISM_13355
Hypothetical protein.
  
     0.580
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
       0.571
ISM_15445
Acetyltransferase, GNAT family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.
  
     0.565
ISM_16145
Hypothetical protein.
  
     0.475
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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