STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_12195COG3264 Small-conductance mechanosensitive channel. (820 aa)    
Predicted Functional Partners:
ISM_12200
Alanyl-transfer RNA synthetase domain protein; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain.
       0.811
ISM_12190
COG0031 Cysteine synthase.
       0.802
ISM_12180
Tellurite resistance protein; COG0477 Permeases of the major facilitator superfamily.
       0.672
ISM_12185
Tellurite resistance protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
       0.642
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.621
ISM_17225
Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components.
     
 0.468
ISM_12175
COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family.
       0.440
ISM_01205
Sensor histidine kinase; COG0591 Na+/proline symporter.
     
 0.417
ISM_05410
COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
   
   0.416
ISM_08965
COG0347 Nitrogen regulatory protein PII.
   
   0.416
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.