Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ISM_12200Alanyl-transfer RNA synthetase domain protein; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain. (238 aa)    
Predicted Functional Partners:
ISM_12195
COG3264 Small-conductance mechanosensitive channel.
       0.820
ISM_12190
COG0031 Cysteine synthase.
  
    0.812
ISM_12180
Tellurite resistance protein; COG0477 Permeases of the major facilitator superfamily.
 
     0.781
ISM_12185
Tellurite resistance protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.
       0.727
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
     
 0.587
ISM_12175
COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family.
       0.519
ISM_09596
Hypothetical protein; COG1204 Superfamily II helicase.
  
     0.424
ISM_03915
2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
  0.401
ISM_16955
Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
     
  0.401
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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