Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISM_12255Flavoprotein; COG0426 Uncharacterized flavoproteins. (245 aa)    
Predicted Functional Partners:
ISM_12260
COG0426 Uncharacterized flavoproteins.
 
    
0.833
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
  
 
 0.765
ISM_12250
Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.553
ISM_12265
Glycine betaine/proline ABC transporter, periplasmic glycinebetaine/proline-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.
       0.550
ISM_05365
Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
  
  
 0.459
ISM_06705
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.424
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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