| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_00215 | ISM_12255 | ISM_00215 | ISM_12255 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Flavoprotein; COG0426 Uncharacterized flavoproteins. | 0.828 |
| ISM_00215 | ISM_12260 | ISM_00215 | ISM_12260 | Hypothetical protein; COG2199 FOG: GGDEF domain. | COG0426 Uncharacterized flavoproteins. | 0.828 |
| ISM_00215 | leuS | ISM_00215 | ISM_02265 | Hypothetical protein; COG2199 FOG: GGDEF domain. | COG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.590 |
| ISM_05365 | ISM_12255 | ISM_05365 | ISM_12255 | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | Flavoprotein; COG0426 Uncharacterized flavoproteins. | 0.462 |
| ISM_05365 | ISM_12260 | ISM_05365 | ISM_12260 | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | COG0426 Uncharacterized flavoproteins. | 0.462 |
| ISM_06130 | ISM_12255 | ISM_06130 | ISM_12255 | Modification methylase (Cytosine-specific methyltransferase; COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Flavoprotein; COG0426 Uncharacterized flavoproteins. | 0.401 |
| ISM_12250 | ISM_12255 | ISM_12250 | ISM_12255 | Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Flavoprotein; COG0426 Uncharacterized flavoproteins. | 0.553 |
| ISM_12250 | ISM_12260 | ISM_12250 | ISM_12260 | Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | COG0426 Uncharacterized flavoproteins. | 0.553 |
| ISM_12250 | ISM_12265 | ISM_12250 | ISM_12265 | Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Glycine betaine/proline ABC transporter, periplasmic glycinebetaine/proline-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components. | 0.407 |
| ISM_12255 | ISM_00215 | ISM_12255 | ISM_00215 | Flavoprotein; COG0426 Uncharacterized flavoproteins. | Hypothetical protein; COG2199 FOG: GGDEF domain. | 0.828 |
| ISM_12255 | ISM_05365 | ISM_12255 | ISM_05365 | Flavoprotein; COG0426 Uncharacterized flavoproteins. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | 0.462 |
| ISM_12255 | ISM_06130 | ISM_12255 | ISM_06130 | Flavoprotein; COG0426 Uncharacterized flavoproteins. | Modification methylase (Cytosine-specific methyltransferase; COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.401 |
| ISM_12255 | ISM_12250 | ISM_12255 | ISM_12250 | Flavoprotein; COG0426 Uncharacterized flavoproteins. | Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.553 |
| ISM_12255 | ISM_12260 | ISM_12255 | ISM_12260 | Flavoprotein; COG0426 Uncharacterized flavoproteins. | COG0426 Uncharacterized flavoproteins. | 0.834 |
| ISM_12255 | ISM_12265 | ISM_12255 | ISM_12265 | Flavoprotein; COG0426 Uncharacterized flavoproteins. | Glycine betaine/proline ABC transporter, periplasmic glycinebetaine/proline-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components. | 0.550 |
| ISM_12255 | leuS | ISM_12255 | ISM_02265 | Flavoprotein; COG0426 Uncharacterized flavoproteins. | COG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.473 |
| ISM_12260 | ISM_00215 | ISM_12260 | ISM_00215 | COG0426 Uncharacterized flavoproteins. | Hypothetical protein; COG2199 FOG: GGDEF domain. | 0.828 |
| ISM_12260 | ISM_05365 | ISM_12260 | ISM_05365 | COG0426 Uncharacterized flavoproteins. | Pyridine nucleotide-disulphide oxidoreductase family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | 0.462 |
| ISM_12260 | ISM_12250 | ISM_12260 | ISM_12250 | COG0426 Uncharacterized flavoproteins. | Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.553 |
| ISM_12260 | ISM_12255 | ISM_12260 | ISM_12255 | COG0426 Uncharacterized flavoproteins. | Flavoprotein; COG0426 Uncharacterized flavoproteins. | 0.834 |