| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_10396 | ISM_12285 | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | Hypothetical membrane protein. | 0.573 |
| ISM_10396 | ISM_12290 | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.471 |
| ISM_10396 | ISM_12295 | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | COG3181 Uncharacterized protein conserved in bacteria. | 0.457 |
| ISM_10396 | ISM_12310 | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | 0.687 |
| ISM_10396 | ISM_12315 | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | Putative succinate dehydrogenase membrane anchor; COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.652 |
| ISM_10396 | ISM_12320 | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.678 |
| ISM_10396 | ISM_12325 | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.647 |
| ISM_10396 | ISM_12330 | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain. | 0.629 |
| ISM_10396 | ISM_12340 | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain. | 0.650 |
| ISM_12285 | ISM_10396 | Hypothetical membrane protein. | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | 0.573 |
| ISM_12285 | ISM_12290 | Hypothetical membrane protein. | Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.927 |
| ISM_12285 | ISM_12295 | Hypothetical membrane protein. | COG3181 Uncharacterized protein conserved in bacteria. | 0.832 |
| ISM_12285 | ISM_12310 | Hypothetical membrane protein. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | 0.786 |
| ISM_12285 | ISM_12315 | Hypothetical membrane protein. | Putative succinate dehydrogenase membrane anchor; COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.828 |
| ISM_12285 | ISM_12320 | Hypothetical membrane protein. | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. | 0.828 |
| ISM_12285 | ISM_12325 | Hypothetical membrane protein. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.821 |
| ISM_12285 | ISM_12330 | Hypothetical membrane protein. | COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain. | 0.825 |
| ISM_12285 | ISM_12340 | Hypothetical membrane protein. | COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain. | 0.826 |
| ISM_12285 | ISM_13340 | Hypothetical membrane protein. | Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.531 |
| ISM_12290 | ISM_10396 | Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | 0.471 |