| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_06675 | ISM_09586 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.786 |
| ISM_06675 | ISM_09941 | Phosphate acetyltransferase; COG0281 Malic enzyme. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.538 |
| ISM_06675 | ISM_12310 | Phosphate acetyltransferase; COG0281 Malic enzyme. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | 0.781 |
| ISM_06675 | ISM_12330 | Phosphate acetyltransferase; COG0281 Malic enzyme. | COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain. | 0.831 |
| ISM_06675 | ISM_12335 | Phosphate acetyltransferase; COG0281 Malic enzyme. | L-carnitine dehydratase/bile acid-inducible protein F; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. | 0.684 |
| ISM_06675 | ISM_12340 | Phosphate acetyltransferase; COG0281 Malic enzyme. | COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain. | 0.830 |
| ISM_06675 | ISM_16800 | Phosphate acetyltransferase; COG0281 Malic enzyme. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.538 |
| ISM_09586 | ISM_06675 | Malate dehydrogenase; COG0281 Malic enzyme. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.786 |
| ISM_09586 | ISM_09941 | Malate dehydrogenase; COG0281 Malic enzyme. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.538 |
| ISM_09586 | ISM_12310 | Malate dehydrogenase; COG0281 Malic enzyme. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | 0.781 |
| ISM_09586 | ISM_12330 | Malate dehydrogenase; COG0281 Malic enzyme. | COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain. | 0.831 |
| ISM_09586 | ISM_12335 | Malate dehydrogenase; COG0281 Malic enzyme. | L-carnitine dehydratase/bile acid-inducible protein F; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. | 0.684 |
| ISM_09586 | ISM_12340 | Malate dehydrogenase; COG0281 Malic enzyme. | COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain. | 0.830 |
| ISM_09586 | ISM_16800 | Malate dehydrogenase; COG0281 Malic enzyme. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.538 |
| ISM_09941 | ISM_06675 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.538 |
| ISM_09941 | ISM_09586 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.538 |
| ISM_09941 | ISM_12310 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | 0.701 |
| ISM_09941 | ISM_12335 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | L-carnitine dehydratase/bile acid-inducible protein F; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family. | 0.713 |
| ISM_09941 | ISM_16800 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.996 |
| ISM_12310 | ISM_06675 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.781 |