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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_12355COG1832 Predicted CoA-binding protein. (156 aa)    
Predicted Functional Partners:
ISM_14405
COG2873 O-acetylhomoserine sulfhydrylase.
   
  0.949
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
   
  0.756
ISM_12345
RNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.589
fur
Transcriptional regulator, Fur family protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
 
    0.587
ISM_14175
COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
  
    0.529
fur-2
Ferric-uptake regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
  
    0.529
ISM_10685
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
   
  0.515
ISM_12350
Hypothetical protein; COG1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB.
       0.490
ISM_04420
Selenium-binding protein, putative.
    
  0.458
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
    
  0.456
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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