STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_12355COG1832 Predicted CoA-binding protein. (156 aa)    
Predicted Functional Partners:
ISM_14405
COG2873 O-acetylhomoserine sulfhydrylase.
   
  0.948
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
   
  0.772
fur
Transcriptional regulator, Fur family protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
 
    0.609
ISM_12345
RNA methyltransferase, TrmH family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.582
ISM_14175
COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
  
    0.554
fur-2
Ferric-uptake regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
  
    0.554
ISM_10685
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
   
  0.546
ISM_04420
Selenium-binding protein, putative.
    
  0.472
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
  0.465
ISM_12350
Hypothetical protein; COG1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB.
       0.456
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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