Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_12410COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis. (96 aa)    
Predicted Functional Partners:
ISM_12415
Hypothetical protein.
       0.845
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.845
ISM_12425
COG3814 Uncharacterized protein conserved in bacteria.
 
    0.751
ISM_11100
COG2960 Uncharacterized protein conserved in bacteria.
  
     0.549
ISM_02530
Hypothetical protein; Belongs to the UPF0262 family.
  
     0.536
ISM_11535
Membrane protein, putative.
  
     0.455
ISM_12430
COG2059 Chromate transport protein ChrA.
       0.442
ISM_13475
Hypothetical protein.
  
     0.419
ISM_12435
Hypothetical protein; COG0607 Rhodanese-related sulfurtransferase.
       0.402
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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